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The effect of endothelin receptor antagonists in the endotoxin-induced uveitis rabbit model
Karaca, Emine Esra; Uzun, Feyzahan; Dilekoz, Ergin; Fincan, Gokce Sevim Ozturk; Ercan, Sevim; Kul, Oguz; Or, Meral (Taylor & Francis Ltd, 2018)Purpose: To investigate the effect of Bosentan (non-selective endothelin receptor antagonist) and BQ123 (ETA receptor antagonist) on intraocular inflammation in an endotoxin-induced uveitis (EIU) rabbit model.Methods: ... -
Effects of chronic L-DOPA administration on neurogenic and endothelium-dependent relaxation responses in rabbit corpus cavernosum
Yildirim, Seniz; Fincan, Gokce Sevim Ozturk; Isli, Fatma; Ercan, Sevim; Sarioglu, Yusuf (Polish Acad Sciences Inst Pharmacology, 2016)Background: Dopamine is a crucial central neurotransmitter that plays a fundamental role in the autonomic and somatic components of penile reflexes in animals and humans. Similar to the erectile responses of dopamine, ... -
Synthesis, structural characterization and myorelaxant activity of 4-naphthylhexahydroquinoline derivatives containing different ester groups
Gunduz, Miyase Gozde; Albayrak, Emine; Isli, Fatma; Fincan, Gokce Sevim Ozturk; Yildirim, Seniz; Simsek, Rahime; Butcher, Ray J. (Serbian Chemical Soc, 2016)The present study reports the synthesis, structural characterization and myorelaxant activity evaluation of a series of 16 novel 4-naphthylhexahydroquinoline derivatives. The compounds were achieved by one-pot microwave-assisted ...